1426660-40-3Relevant academic research and scientific papers
TMPZnOPiv?LiCl: A new base for the preparation of air-stable solid zinc pivalates of sensitive aromatics and heteroaromatics
Stathakis, Christos I.,Manolikakes, Sophia M.,Knochel, Paul
, p. 1302 - 1305 (2013)
A wide range of aryl and heteroaryl zinc pivalates bearing sensitive functionalities were prepared by selective metalation using TMPZnOPiv?LiCl, a new hindered zinc amide base. The new zinc reagents are easy-to-handle solids, which maintain their activity almost entirely (>95%) after 4 h of air exposure and smoothly undergo Negishi cross-couplings and reactions with various electrophiles such as Cu(I)-catalyzed acylations and allylations.
