1426686-07-8Relevant academic research and scientific papers
BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME
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Paragraph 00406; 00421; 00422, (2015/06/11)
Described herein are compounds capable of modulating one or more biomolecules substantially simultaneously, e.g., modulating two or more binding domains (e.g., bromodomains) on a protein or on different proteins. For example, in one aspect, a bivalent compound or a pharmaceutically acceptable salt, stereoisomer, metabolite, or hydrate thereof is provided. In another aspect, a method of treating a disease associated with a protein having tandem bromodomains in a patient in need thereof is provided. The method comprises administering to the patient the bivalent compound as described.
BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME
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, (2013/03/28)
Described herein are compounds capable of modulating one or more biomolecules substantially simultaneously, e.g., modulating two or more binding domains (e.g., bromodomains) on a protein or on different proteins.
