1426822-68-5Relevant articles and documents
Chemical tagging of a drug target using 5-sulfonyl tetrazole
Otsuki, Satsuki,Nishimura, Shinichi,Takabatake, Hisae,Nakajima, Kozue,Takasu, Yasuaki,Yagura, Toru,Sakai, Yuki,Hattori, Akira,Kakeya, Hideaki
, p. 1608 - 1611 (2013/04/10)
Irreversible modification is one of the most promising strategies to identify cellular receptors of bioactive small molecules. Here we report that receptor proteins can be chemically tagged using a 5-sulfonyl tetrazole probe. 5-Sulfonyl tetrazole easily a