75178-90-4

Basic information

• Product Name: 5-(BOC-AMINO)-1-PENTANOL
• Synonyms: 5-(Boc-Amino)-1-Pentanoll;5-Aminopentan-1-ol, N-BOC protected 95%;N-BOC-5-AMINO-1-PENTANOL;Boc-NH-Pen-OH;N-t-Butyloxycarbonyl-5-hydroxy-pentylamine;1-(tert-Butoxycarbonylamino)-5-pentanol;5-(Boc-amino)pentan-1-ol;5-(N-tert-Butoxycarbonyl)amino-1-pentanol
• CAS NO: 75178-90-4
• Molecular Formula: C₁₀H₂₁NO₃
• Molecular Weight: 203.28
• Product Categories: All Aliphatics;Aliphatics
• Mol File: 75178-90-4.mol
• Article Data: 81

Chemical Properties

• Boiling Point: 318.4 °C at 760 mmHg
• Flash Point: >109°C
• Appearance: Pale Yellow Oil
• Density: 1.00 g/mL at 20 °C(lit.)
• Vapor Pressure: 3E-05mmHg at 25°C
• Refractive Index: n20/D 1.45
• Storage Temp.: 2-8°C
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• PKA: 12.88±0.46(Predicted)
• Water Solubility: Difficult to mix in water.
• Sensitive: Moisture Sensitive
• BRN: 3603659
• CAS DataBase Reference: 5-(BOC-AMINO)-1-PENTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(BOC-AMINO)-1-PENTANOL(75178-90-4)
• EPA Substance Registry System: 5-(BOC-AMINO)-1-PENTANOL(75178-90-4)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 23-24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 75178-90-4(Hazardous Substances Data)

Usage

Description

5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

Pale Yellow Oil

Uses

Different sources of media describe the Uses of 75178-90-4 differently. You can refer to the following data:
1. Linker (anthraquinone-oligopeptide)
2. 5-(Boc-amino)-1-pentanol may also be used as non-limiting linkers.

Synthesis Reference(s)

Synthetic Communications, 20, p. 773, 1990 DOI: 10.1080/00397919008052321

InChI:InChI=1/C10H21NO3/c1-10(2,3)14-9(13)11-7-5-4-6-8-12/h12H,4-8H2,1-3H3,(H,11,13)

Upstream product

• 2508-29-4 5-hydroxypentylamine 
• 34619-03-9 tert-butyldicarbonate 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 27219-07-4 5-(N-tert-butyloxycarbonyl)aminopentanoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1204225-81-9 C₂₅H₃₅NO₅ 

Downstream Products

• 83948-54-3 tert-butyl (5-bromopentyl)carbamate 
• 189341-19-3 2-Chloro-benzenesulfonic acid 3-(5-tert-butoxycarbonylamino-pentyloxy)-5-methyl-phenyl ester 
• 131667-57-7 tert-butyl 1,2,3,4-tetrahydro-1-pyridinecarboxylate 
• 34987-10-5 N¹-benzyl-N¹-methylpentane-1,5-diamine 
• 849473-06-9 [5-(benzyl-methyl-amino)-pentyl]-carbamic acid tert-butyl ester 
• 892414-07-2 C₁₆H₂₄N₂O₅ 
• 142342-55-0 diethyl {5-[(tert-butoxycarbonyl)amino]pentyl }-propanedioate 
• 95388-79-7 N-[(tert-butoxy)carbonyl]-4-chloro-butylamine 
• 116861-31-5 tert-butyl N-(3-chloropropyl)carbamate 
• 1204225-81-9 C₂₅H₃₅NO₅ 
• 1346656-98-1 tert-butyl 4-((phenylthio)carbonyl)butylbenzylcarbamate 
• 1346657-00-8 tert-butyl N-benzyl-5-(dimethylphenylsilyl)-5-oxopentylcarbamate 
• 213771-60-9 tert-Butyl N-benzyl-5-hydroxypentylcarbamate 
• 213771-94-9 5-(N-tert-Butoxycarbonyl-N-phenylmethylamino)-pentanoic acid 

Relevant articles and documents

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