1426832-63-4

Upstream product

• 18437-68-8 tert-butyl N-(4-methoxyphenyl)carbamate 
• 157496-75-8 tert-butyl (2-iodo-4-methoxyphenyl)carbamate 

Downstream Products

• 2731-01-3 (±)-5-methoxy-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indole 
• 128368-43-4 2-isopropenyl-4-methoxyaniline 
• 128368-44-5 (2-Isopropenyl-4-methoxy-phenyl)-carbamic acid methyl ester 
• 128368-45-6 [(2-Isopropenyl-4-methoxy-phenyl)-methoxycarbonyl-amino]-acetic acid methyl ester 
• 128368-46-7 [(2-Isopropenyl-4-methoxy-phenyl)-methoxycarbonyl-amino]-acetic acid 

Relevant academic research and scientific papers

Synthesis of (±)-esermethole via an intramolecular carbamoylketene-alkene [2+2] cycloaddition

A synthesis of (±)-esermethole (2), a synthetic precursor of physostigmine (1), has been accomplished by using an intramolecular carbamoylketene-alkene [2+2] cycloaddition followed by nitrone-mediated regioselective ring expansion for the construction of the basic carbon framework of 2 as the key steps.