1426847-83-7

Basic information

• Product Name: (+)-2-[(1S)-1-(3,4-dimethoxybenzoyl)-2-methoxy-1-methyl-2-oxoethyl]hydrazinecarboxylic acid benzyl ester
• Synonyms: (+)-2-[(1S)-1-(3,4-dimethoxybenzoyl)-2-methoxy-1-methyl-2-oxoethyl]hydrazinecarboxylic acid benzyl ester
• CAS NO: 1426847-83-7
• Molecular Weight: 402.447
• Mol File: 1426847-83-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+)-2-[(1S)-1-(3,4-dimethoxybenzoyl)-2-methoxy-1-methyl-2-oxoethyl]hydrazinecarboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-2-[(1S)-1-(3,4-dimethoxybenzoyl)-2-methoxy-1-methyl-2-oxoethyl]hydrazinecarboxylic acid benzyl ester(1426847-83-7)
• EPA Substance Registry System: (+)-2-[(1S)-1-(3,4-dimethoxybenzoyl)-2-methoxy-1-methyl-2-oxoethyl]hydrazinecarboxylic acid benzyl ester(1426847-83-7)

Safety Data

• Hazardous Substances Data: 1426847-83-7(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 168165-94-4 methyl 3-(3,4-dimethoxyphenyl)-2-methyl-3-oxopropanoate 
• 74053-93-3 methyl 3-(3,4-dimethoxyphenyl)-3-oxopropionate 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 1426847-82-6 (S)-benzyl 2-(1-(3,4-dimethoxyphenyl)-3-methoxy-2-methyl-1,3-dioxopropan-2-yl)hydrazinecarboxylate 
• 1281895-44-0 (+)-1-[(1S)-1-(3,4-dimethoxybenzoyl)-2-methoxy-1-methyl-2-oxoethyl]-1,2-hydrazinedicarboxylic acid 1,2-di-tert-butylester 

Downstream Products

• 302-53-4 S(-)-carbidopa 

Relevant articles and documents

Chiral lithium binaphtholate for enantioselective amination of acyclic α-alkyl-β-keto esters: Application to the total synthesis of L-carbidopa

A chiral lithium binaphtholate catalyzes the enantioselective amination of α-alkyl-β-keto esters with azodicarboxylates to produce optically active α,α-disubstituted α-amino acid derivatives in high yields and with good to high enantioselectivities. A stoichiometric amount of lithium hydroxide efficaciously improved both the reactivity and enantioselectivity of amination. The resulting aminated product is readily convertible to L-carbidopa.