1426919-97-2

Basic information

• Product Name: C₁₂H₈OS
• Synonyms: C₁₂H₈OS
• CAS NO: 1426919-97-2
• Molecular Weight: 200.261
• Mol File: 1426919-97-2.mol

Chemical Properties

• CAS DataBase Reference: C₁₂H₈OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₈OS(1426919-97-2)
• EPA Substance Registry System: C₁₂H₈OS(1426919-97-2)

Safety Data

• Hazardous Substances Data: 1426919-97-2(Hazardous Substances Data)

Upstream product

• 540-38-5 p-Iodophenol 
• 40231-03-6 2-(trimethylsilylethynyl)thiophene 

Relevant articles and documents

Phenoxide-mediated Sonogashira coupling of trimethylsilylalkynes and aryliodides: Practical synthesis of phenolic-hydroxy-substituted diarylethynes and 1,4-diarylbutadiynes

We successfully synthesized phenolic-hydroxy-substituted diarylethynes and 1,4-diarylbutadiynes from trimethylsilylalkynes and aryliodides via silyl-group-migration-induced deprotection of alkynes and the usual Sonogashira coupling. The phenol moiety, which works as a desilylating agent, can be attached to any position in the coupling partner. This improvement for Sonogashira coupling would be highly effective, especially when the coupling partner has a phenol moiety. Additionally, the stability of the migrated silyl moiety on the ethynylation of 2-iodophenol is discussed.