1427054-53-2Relevant articles and documents
Organocatalytic 1,4-conjugate addition of ascorbic acid to α,β-unsaturated aldehydes: Bio-inspired total syntheses of leucodrin, leudrin and proposed structure of dilaspirolactone
Wang, Zhaofeng,Zhao, Kun,Fu, Junkai,Zhang, Junlin,Yin, Weiyu,Tang, Yefeng
supporting information, p. 2093 - 2097 (2013/04/23)
The organocatalytic additions of ascorbic acid to various α,β-unsaturated aldehydes via tandem 1,4-conjugate addition/hemiacetalization/hemiketalization were developed, which provided a rapid entry into the 5-5-5 spirodilactone cores of a family of ascorbylated natural products. Based on the described chemistry, total syntheses of leucodrin, leudrin and the proposed structure of dilaspirolactone were achieved. The Royal Society of Chemistry 2013.
