1427086-32-5Relevant articles and documents
Nickel-Catalyzed Reductive Coupling for Transforming Unactivated Aryl Electrophiles into β-Fluoroethylarenes
Yang, Yi,Luo, Gen,Li, Youlin,Tong, Xia,He, Mengmeng,Zeng, Hongyao,Jiang, Yan,Liu, Yingle,Zheng, Yubin
, p. 156 - 162 (2020)
We report herein a facile synthetic method for converting unactivated (hetero)aryl electrophiles into β-fluoroethylated (hetero)arenes via nickel-catalyzed reductive cross-couplings. This coupling reaction features the involvement of FCH2CHsub
A monofluorophosphate ethyl substituted aromatic compound preparation method (by machine translation)
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Paragraph 0177-0181, (2018/04/02)
The present invention provides a mono ethyl substituted aromatic compound preparation method, which belongs to the technical field of preparation of fluorine-containing organic molecules. The preparation method is the reaction solvent and under the nitrogen atmosphere, in order to 1 - fluoro - 2 - ethyl iodide and through the weak base after activating the aryl boric acid as the raw material, the nickel catalyst and bipyridines ligand under the action of the catalytic system, heating the reaction reaches the end point, the separation, purification mono ethyl substituted aromatic compound. Preparation method of this invention adopts the cheap and easy nickel catalyst and bipyridines ligand is a catalytic system, the realization of the mono ethyl to the orientation of the aromatic group introduced, thus high-efficient preparation to obtain mono ethyl substituted aromatic compound. The method not only mild reaction conditions, raw material sources are wide, low cost, simple reaction steps, the reaction scale is easy to amplification, product separation is simple, has the advantage of being suitable for industrial production. (by machine translation)
COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS
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Page/Page column 230, (2013/03/26)
The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the