1427158-05-1

Basic information

• Product Name: 2-(4-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one
• Synonyms: 2-(4-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one
• CAS NO: 1427158-05-1
• Molecular Weight: 241.249
• Mol File: 1427158-05-1.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one(1427158-05-1)
• EPA Substance Registry System: 2-(4-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one(1427158-05-1)

Safety Data

• Hazardous Substances Data: 1427158-05-1(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 159326-69-9 1-aminopyrrole-2-carboxamide 

Relevant articles and documents

A tandem copper (II)-promoted synthesis of 2-substituted pyrrolo[2,1-f][1,2,4] triazin-4(3H)-ones

An efficient tandem method for the annulation of 1-amino-1H-pyrrole-2- amides with various substituted benzaldehydes, heteroaryl aldehydes, alkyl aldehydes or even acetals, promoted by cupric chloride, to synthesize 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones is reported. This approach provides a useful method for constructing the privileged structure in medicinal chemistry. Electron-donating groups on both partners could accelerate the reaction.