1427296-19-2

Basic information

• Product Name: 3-amino-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one
• Synonyms: 3-amino-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one
• CAS NO: 1427296-19-2
• Molecular Weight: 253.301
• Mol File: 1427296-19-2.mol

Chemical Properties

• CAS DataBase Reference: 3-amino-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one(1427296-19-2)
• EPA Substance Registry System: 3-amino-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one(1427296-19-2)

Safety Data

• Hazardous Substances Data: 1427296-19-2(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 38435-51-7 N-hydroxy-4-methoxy-benzenecarboximidoyl chloride 
• 874-90-8 4-methoxybenzonitrile 
• 98-86-2 acetophenone 

Downstream Products

• 32664-28-1 3-(4-methoxyphenyl)-5-phenyl-1H-pyrazole 

Relevant articles and documents

Copper on iron promoted one-pot synthesis of β-aminoenones and 3,5-disubstituted pyrazoles

The reaction of hydroximoyl chlorides with acetylenes in the presence of a copper on iron bimetallic system leads to β-aminoenones via reductive ring opening of isoxazole intermediates. The valuable β-aminoenone building blocks can be isolated or transformed into pyrazoles with the addition of hydrazine in a straightforward one-pot procedure.

Copper-catalyzed aldol-type addition of ketones to aromatic nitriles: A simple approach to enaminone synthesis

An efficient method for the synthesis of enaminones is described. The aldol-type addition of ketones to aromatic nitriles proceeded smoothly in the presence of a simple copper catalyst system (CuI-2,2′-bipyridine-NaO tBu) in N,N-dimethylformamide. Enaminones in satisfactory to excellent yields were produced using this technique. The Royal Society of Chemistry 2013.