1427299-87-3Relevant academic research and scientific papers
Ruthenium(II)-catalyzed regioselective reductive coupling of α-imino esters with dienes
Zhu, Shujie,Lu, Xiaoxia,Luo, Yueting,Zhang, Wei,Jiang, Huanfeng,Yan, Ming,Zeng, Wei
supporting information, p. 1440 - 1443 (2013/06/27)
A method for the highly regioselective reductive coupling reaction of N-aryl-α-imino esters with dienes is described. The method utilizes the RuHCl(CO)(PPh3)3/iPrOH catalytic system under an Ar atmosphere and provides α-branched allylic α-amino acid derivatives. Application of this transformation to the concise synthesis of a natural plant growth regulator is demonstrated.
