1427309-26-9

Basic information

• Product Name: tert-butyl 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetate
• Synonyms: tert-butyl 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetate
• CAS NO: 1427309-26-9
• Molecular Weight: 606.144
• Mol File: 1427309-26-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetate(1427309-26-9)
• EPA Substance Registry System: tert-butyl 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetate(1427309-26-9)

Safety Data

• Hazardous Substances Data: 1427309-26-9(Hazardous Substances Data)

Upstream product

• 220394-97-8 4-(benzyloxycarbonylamino)-1-(tert-butoxycarbonyl)piperidine 
• 182223-54-7 piperidin-4-ylcarbamic acid benzyl ester 
• 1427058-43-2 benzyl N-[1-(2-fluoropentyl)piperidin-4-yl]carbamate 
• 1427058-44-3 1-(2-fluoropentyl)piperidin-4-amine 
• 886500-26-1 2-(bromomethyl)-1-chloro-3-(trifluoromethyl)benzene 
• 1427309-24-7 (3S,4R)-1-benzyl-3-[2-(tert-butoxy)-2-oxoethyl]-4-methylpyrrolidine-3-carboxylic acid 
• 1427309-25-8 tert-butyl 2-[(3S,4R)-1-benzyl-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetate 
• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 
• 1427309-47-4 (4-methoxyphenyl)methyl (3R,4R)-1-benzyl-4-methylpyrrolidine-3-carboxylate 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 110-62-3 pentanal 
• 1427058-85-2 (4-methoxyphenyl)methyl (3R,4R)-1-benzyl-4-methylpyrrolidine-3-carboxylate (-)-dibenzoyl-L-tartrate 
• 817-70-9 2-fluoro-pentanal 

Downstream Products

• 1427058-31-8 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl}-4-methylpyrrolidin-3-yl]acetic acid 

Relevant articles and documents

PYRROLIDINE-3-YLACETIC ACID DERIVATIVE

A compound represented by formula (1) or a pharmaceutically acceptable salt thereof has an inhibitory effect in the fractalkine-CX3CR1 pathway: wherein R represents a C1-6 alkyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group A, a C3-8 cycloalkyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group A, or a C3-8 cycloalkenyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group A, X represents a C1-6 alkyl group, Y and Z are the same or different from each other and each represents a halogen atom or a C1-6 alkyl group unsubstituted or having 1 to 3 substituents selected from Substituent Group B, n represents 0 or 1, Substituent Group A consists of halogen atoms, and Substituent Group B consists of halogen atoms.