1427435-51-5

Basic information

• Product Name: 7-(4-chlorophenyl)-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-thione
• CAS NO: 1427435-51-5
• Molecular Weight: 278.765
• Mol File: 1427435-51-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-(4-chlorophenyl)-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4-chlorophenyl)-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-thione(1427435-51-5)
• EPA Substance Registry System: 7-(4-chlorophenyl)-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-thione(1427435-51-5)

Safety Data

• Hazardous Substances Data: 1427435-51-5(Hazardous Substances Data)

Upstream product

• 62903-14-4 4-(3-chlorophenyl)-4-oxobutyric acid 
• 1079-73-8 6-(4-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone 
• 17356-08-0 thiourea 
• 66122-52-9 6-(4-chloro-phenyl)-2-hydroxymethyl-4,5-dihydro-2H-pyridazin-3-one 
• 108-90-7 chlorobenzene 
• 3984-34-7 4-(4-chlorophenyl)-4-oxobutanoic acid 

Relevant articles and documents

Design, synthesis and antihypertensive screening of novel pyridazine substituted s-triazin-2-imine/one/thione derivatives

Some new 7-substituted-phenyl-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-imine/one/thione derivatives were synthesized by a sequence of reactions starting from appropriate aryl hydrocarbons. The final compounds were screened for antihypertensive activities by non-invasive method using Tail Cuff method. All the test compounds showed significant antihypertensive activity; 7-(biphenyl-4-yl)-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-imine (4p) exhibited antihypertensive activity more than the reference standard drugs.