142762-00-3

Basic information

• Product Name: Hexanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester
• CAS NO: 142762-00-3
• Molecular Formula: C14H18N2O3
• Molecular Weight: 262.309
• Mol File: 142762-00-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester(142762-00-3)
• EPA Substance Registry System: Hexanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester(142762-00-3)

Safety Data

• Hazardous Substances Data: 142762-00-3(Hazardous Substances Data)

Upstream product

• 100-34-5 benzene diazonium chloride 
• 3249-68-1 ethyl butyroyl acetate 
• 62-53-3 aniline 

Downstream Products

• 145664-34-2 2-(1-Oxy-pyridine-3-carbonyl)-4-(phenyl-hydrazono)-5-propyl-2,4-dihydro-pyrazol-3-one 
• 145664-26-2 4-(Phenyl-hydrazono)-5-propyl-2-(pyridine-3-carbonyl)-2,4-dihydro-pyrazol-3-one 

Relevant articles and documents

Potentially active hypoglycemic agents from N1-nicotinoyl-2-pyrazolin-5-one derivatives and their N1-(oxynicotinoyl) analogues

Several ethyl 2,3-dioxohexanoate 2-arylhydrazone derivatives were obtained via coupling of the appropriate diazonium chlorides with ethyl butanoylacetate. Acetic acid-mediated cyclization of these products with N1-nicotinoyl and/or N1-(oxynicotinoyl)hydrazine derivatives gave a new series of 4-arylhydrazono-3-(n-propyl)-N1-nicotinoyl-2-pyrazolin-5-ones (Va-h) as well as their N1-(oxynicotinoyl) analogues (VIa-h). The structure of the prepared compounds was confirmed on the basis of elemental and spectral data. The hypoglycemic effect, antibacterial activity and toxicity of these agents were evaluated and discussed.