1427731-11-0

Basic information

• Product Name: diethyl 2-(6-(benzyloxy)hexyl)-2-(cyclohexylmethyl)malonate
• Synonyms: diethyl 2-(6-(benzyloxy)hexyl)-2-(cyclohexylmethyl)malonate
• CAS NO: 1427731-11-0
• Molecular Weight: 446.627
• Mol File: 1427731-11-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 2-(6-(benzyloxy)hexyl)-2-(cyclohexylmethyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(6-(benzyloxy)hexyl)-2-(cyclohexylmethyl)malonate(1427731-11-0)
• EPA Substance Registry System: diethyl 2-(6-(benzyloxy)hexyl)-2-(cyclohexylmethyl)malonate(1427731-11-0)

Safety Data

• Hazardous Substances Data: 1427731-11-0(Hazardous Substances Data)

Upstream product

• 2550-36-9 Cyclohexylmethyl bromide 
• 105-53-3 diethyl malonate 
• 54247-27-7 1-bromo-6-benzyloxyhexane 
• 29805-59-2 diethyl (cyclohexylmethyl)propanedioate 

Downstream Products

• 1427731-13-2 5-(cyclohexylmethyl)-5-(6-hydroxyhexyl)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1427731-07-4 5-(cyclohexylmethyl)-5-(6-fluorohexyl)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1427731-12-1 5-(6-(benzyloxy)hexyl)-5-(cyclohexylmethyl)pyrimidine-2,4,6(1H,3H,5H)-trione 

Relevant articles and documents

18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS

The present invention relates generally to the field of diagnostic methods. More specifically, the present invention pertains to certain 18F-labelled barbiturate compounds of the following formula (collectively referred to herein as "18F-fluorinated barbiturate compounds" and "18FBAR compounds") that bind to metals, for example, metals associated with protein aggregates, and as such are useful as imaging agents for positron emission imaging (e.g., positron emission tomography (PET) imaging) used in the diagnosis and monitoring of conditions involving these aggregates, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD). These compounds also bind strongly to GABAA receptors and hence are also useful as imaging agents for positron emission tomography (PET) imaging used in the diagnosis, monitoring and study of diseases involving dis-regulation of these receptors, including epilepsy, schizophrenia, and mood disorders (e.g., anxiety).