1427798-08-0Relevant articles and documents
Dual gold catalysis: A novel synthesis of bicyclic and tricyclic pyrroles from n -propargyl ynamides
Tokimizu, Yusuke,Wieteck, Marcel,Rudolph, Matthias,Oishi, Shinya,Fujii, Nobutaka,Hashmi, A. Stephen K.,Ohno, Hiroaki
, p. 604 - 607 (2015)
Various N-propargyl ynamides were converted to bicylic and tricyclic pyrroles by the use of a cationic dual-activation gold catalyst. This reaction starts with the nucleophilic addition of a gold acetylide onto an ynamide triple bond at the ?2-position of the nitrogen atom. Thus, gold vinylidene is formed, and then a second cyclization takes place. The formation of the gold vinylidene is indicated by the evidence that not only aryl ynamides but also alkyl ynamides undergo C-H activation in these reactions.