1428123-07-2Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of a series of benzo[ de ][1,7]naphthyridin-7(8 H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors
Ye, Na,Chen, Chuan-Huizi,Chen, Tiantian,Song, Zilan,He, Jin-Xue,Huan, Xia-Juan,Song, Shan-Shan,Liu, Qiufeng,Chen, Yi,Ding, Jian,Xu, Yechun,Miao, Ze-Hong,Zhang, Ao
, p. 2885 - 2903 (2013/06/04)
A series of benzo[de][1,7]naphthyridin-7(8H)-ones possessing a functionalized long-chain appendage have been designed and evaluated as novel PARP1 inhibitors. The initial effort led to the first-generation PARP1 inhibitor 26 bearing a terminal phthalazin-
