1428144-25-5

Basic information

• Product Name: 4-cyclohexyl-5-phenylthieno[3,2-b]pyridin-7(4H)-one
• Synonyms: 4-cyclohexyl-5-phenylthieno[3,2-b]pyridin-7(4H)-one
• CAS NO: 1428144-25-5
• Molecular Weight: 309.432
• Mol File: 1428144-25-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyclohexyl-5-phenylthieno[3,2-b]pyridin-7(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyclohexyl-5-phenylthieno[3,2-b]pyridin-7(4H)-one(1428144-25-5)
• EPA Substance Registry System: 4-cyclohexyl-5-phenylthieno[3,2-b]pyridin-7(4H)-one(1428144-25-5)

Safety Data

• Hazardous Substances Data: 1428144-25-5(Hazardous Substances Data)

Upstream product

• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 7311-64-0 3-bromothiophene-2-carboxylic acid 
• 26137-08-6 methyl 3-bromothiophene-2-carboxylate 
• 1204601-58-0 1-(3-bromothiophen-2-yl)-3-phenylprop-2-yn-1-one 
• 108-91-8 cyclohexylamine 
• 536-74-3 phenylacetylene 
• 25796-68-3 3-bromo-thiophene-2-carbonyl chloride 

Relevant articles and documents

Efficient synthesis of novel thieno[3,2-b]-, [2,3-c]- and [3,2-c]pyridones by Sonogashira coupling of bromothiophenes with terminal alkynes and subsequent intramolecular C-N bond-forming reaction

The coupling of bromothiophenes with terminal alkynes using triethylamine or diisopropyl amine under Sonogashira conditions (PdCl2(PPh 3)2, CuI) followed by subsequent addition of amines or ammonium to the intermediate thienyl acetylenes represents a novel access to a wide range of thieno[3,2-b]-, [2,3-c]-, and [3,2-c]pyridones under basic conditions and in excellent yields.