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1428228-75-4

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1428228-75-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1428228-75-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,8,2,2 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1428228-75:
(9*1)+(8*4)+(7*2)+(6*8)+(5*2)+(4*2)+(3*8)+(2*7)+(1*5)=164
164 % 10 = 4
So 1428228-75-4 is a valid CAS Registry Number.

1428228-75-4Downstream Products

1428228-75-4Relevant academic research and scientific papers

Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators

Chae, Eunhee,Shin, Yong-Je,Ryu, Eun-Ju,Ji, Mi Kyung,Ryune Cho, Nahm,Lee, Ki-Ho,Jeong, Hyun Ji,Kim, Soo-Jin,Choi, Yeonjung,Seok Oh, Kyung,Park, Chun-Eung,Soo Yoon, Young

, p. 2134 - 2139 (2013/05/09)

Development of SAR in a 5-aryl-3-acylpyridinyl-pyrazoles and 1-aryl-4-acylpyridinyl imidazoles series of mGlu5 receptor negative allosteric modulators (mGluR5 NAMs) using a functional cell-based assay is described in this Letter. Analysis of the Ligand-lipophilic efficiency (LipE) of compounds provided new insight for the design of potent mGluR5 negative allosteric modulators with anti-depressant activities.

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