871362-70-8

Basic information

• Product Name: 5-(4-fluoro-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid ethyl ester
• Synonyms: 5-(4-fluoro-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid ethyl ester
• CAS NO: 871362-70-8
• Molecular Weight: 262.284
• Mol File: 871362-70-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(4-fluoro-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-fluoro-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid ethyl ester(871362-70-8)
• EPA Substance Registry System: 5-(4-fluoro-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid ethyl ester(871362-70-8)

Safety Data

• Hazardous Substances Data: 871362-70-8(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 
• 456-03-1 1-(4-fluorophenyl)propan-1-one 
• 1224924-43-9 C₁₃H₁₃FO₄ 
• 60-34-4 methylhydrazine 

Downstream Products

• 1428228-75-4 C₁₇H₁₄F₂N₄O 
• 1428228-76-5 C₁₇H₁₄ClFN₄O 
• 1428228-77-6 C₁₇H₁₅FN₄O 
• 1428228-78-7 C₁₈H₁₇FN₄O 
• 1428228-79-8 C₁₇H₁₄ClFN₄O 
• 1428228-80-1 C₁₇H₁₄F₂N₄O 
• 1428228-81-2 C₁₆H₁₃ClFN₅O 
• 1428228-82-3 C₁₆H₁₅FN₄OS 
• 1428228-83-4 C₁₆H₁₅FN₄OS 
• 1428228-47-0 C₁₈H₁₇FN₄O 
• 1428228-69-6 C₁₈H₁₇FN₄O 
• 1428228-70-9 C₁₈H₁₇FN₄O 
• 1428228-71-0 C₁₇H₁₄ClFN₄O 
• 1428228-72-1 C₁₈H₁₄F₄N₄O 

Relevant articles and documents

Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators

Development of SAR in a 5-aryl-3-acylpyridinyl-pyrazoles and 1-aryl-4-acylpyridinyl imidazoles series of mGlu5 receptor negative allosteric modulators (mGluR5 NAMs) using a functional cell-based assay is described in this Letter. Analysis of the Ligand-lipophilic efficiency (LipE) of compounds provided new insight for the design of potent mGluR5 negative allosteric modulators with anti-depressant activities.