1428245-05-9

Basic information

• Product Name: N-(4-chloro-2-(2-hydroxybenzoyl)phenyl)-2,2,2-trifluoroacetamide
• Synonyms: N-(4-chloro-2-(2-hydroxybenzoyl)phenyl)-2,2,2-trifluoroacetamide
• CAS NO: 1428245-05-9
• Molecular Weight: 343.69
• Mol File: 1428245-05-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-chloro-2-(2-hydroxybenzoyl)phenyl)-2,2,2-trifluoroacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chloro-2-(2-hydroxybenzoyl)phenyl)-2,2,2-trifluoroacetamide(1428245-05-9)
• EPA Substance Registry System: N-(4-chloro-2-(2-hydroxybenzoyl)phenyl)-2,2,2-trifluoroacetamide(1428245-05-9)

Safety Data

• Hazardous Substances Data: 1428245-05-9(Hazardous Substances Data)

Upstream product

• 69559-40-6 N-(2-benzoyl-4-chlorophenyl)-2,2,2-trifluoroacetamide 

Relevant articles and documents

Broadening the catalyst and reaction scope of regio- and chemoselective C-H oxygenation: A convenient and scalable approach to 2-acylphenols by intriguing Rh(ii) and Ru(ii) catalysis

A unique Rh(ii) and Ru(ii) catalyzed C-H oxygenation of aryl ketones and other arenes has been developed for the facile synthesis of diverse functionalized phenols. The reaction demonstrates excellent reactivity, regio- and chemoselectivity, good functional group compatibility and high yields. The practicality of this method has been proved by gram-scale synthesis of a few different 2-acylphenols. Its utility has been well exemplified in further applications in heterocycle synthesis and direct modifications of drug Fenofibrate.