1428252-95-2

Upstream product

• 158654-96-7 4-(1H-imidazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 1428252-94-1 tert-butyl 4-(4-bromo-1H-imidazol-2-yl)piperidine-1-carboxylate 
• 1001200-60-7 2-(4-fluoro-3-methylphenyl)-4,4,5,5-tetramethyl[1,3,2]dioxaborolane 
• 1226803-00-4 tert-butyl 4-(4-bromo-1-(2-hydroxyethyl)-1H-imidazol-2-yl)piperidine-1-carboxylate 
• 139911-27-6 4-fluoro-3-methylphenyl boronic acid 

Downstream Products

• 1428253-11-5 tert-butyl 4-(4-amino-6-(4-(4-(4-fluoro-3-methylphenyl)-1-(2-hydroxyethyl)-1H-imidazol-2-yl)piperidin-1-yl)pyrimidin-5-yl)-1H-pyrazole-1-carboxylate 
• 1428250-28-5 2-(2-(1-(6-amino-5-(1H-pyrazol-4-yl)pyrimidin-4-yl)piperidin-4-yl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-1-yl)ethanol 
• 1446104-05-7 2-(2-(1-(6-amino-5-bromopyrimidin-4-yl)piperidin-4-yl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-1-yl)ethanol 
• 1428253-12-6 tert-butyl 4-(4-amino-6-(4-(4-(4-fluoro-3-methylphenyl)-1-(2-((methylsulfonyl)oxy)ethyl)-1H-imidazol-2-yl)piperidin-1-yl)pyrimidin-5-yl)-1H-pyrazole-1-carboxylate 
• 1428250-29-6 6-(4-(1-(2-(cyclopropylamino)ethyl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-(1H-pyrazol-4-yl)pyrimidin-4-amine 
• 1428253-14-8 2-[4-(4-fluoro-3-methylphenyl)-2-piperidin-4-yl-imidazol-1-yl]ethyl-dimethylamine 

Relevant academic research and scientific papers

NOVEL IMIDAZOLE AMINES AS MODULATORS OF KINASE ACTIVITY

The invention provides novel imidazole amine compounds according to Formula (I) and Formula (II) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.