158654-96-7

Basic information

• Product Name: 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
• Synonyms: 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;tert-Butyl 4-(1H-imidazol-2-yl)piperidine-1-carboxylate;4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1;4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;1-Boc-4-imidazol-2-yl-piperidine, 98%
• CAS NO: 158654-96-7
• Molecular Formula: C13H21N3O2
• Molecular Weight: 251.328
• Mol File: 158654-96-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 435°C at 760 mmHg
• Flash Point: 216.9°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 9.06E-08mmHg at 25°C
• Refractive Index: 1.532
• PKA: 14.07±0.10(Predicted)
• CAS DataBase Reference: 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester(158654-96-7)
• EPA Substance Registry System: 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester(158654-96-7)

Safety Data

• Hazardous Substances Data: 158654-96-7(Hazardous Substances Data)

Usage

General Description

4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester is a chemical compound that is commonly used in pharmaceutical research. It belongs to the class of piperidinecarboxylic acid esters and contains an imidazole ring. 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester is known for its potential applications in the development of new drugs or as a building block in medicinal chemistry. Its specific properties and potential biological activities make it an important target for drug discovery and development. The chemical structure of 4-(1H-Imidazol-2-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester makes it a valuable compound for further investigation in drug design and synthesis.

InChI:InChI=1/C13H21N3O2/c1-13(2,3)18-12(17)16-8-4-10(5-9-16)11-14-6-7-15-11/h6-7,10H,4-5,8-9H2,1-3H3,(H,14,15)

Upstream product

• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 131543-46-9 Glyoxal 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 158654-94-5 tert-butyl 4-(1H-imidazol-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate 

Downstream Products

• 90747-46-9 4-(1H-lmidazol-2-yl)piperidine dihydrochloride 
• 1428252-97-4 4-[1-(2-azetidin-1-ylethyl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-2-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 1428253-42-2 4-(1-(2-(azetidin-1-yl)ethyl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-2-yl)piperidine 
• 1428253-14-8 2-[4-(4-fluoro-3-methylphenyl)-2-piperidin-4-yl-imidazol-1-yl]ethyl-dimethylamine 
• 1428252-95-2 4-[4-(4-fluoro-3-methylphenyl)-1-(2-hydroxyethyl)-1H-imidazol-2-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 1428250-29-6 6-(4-(1-(2-(cyclopropylamino)ethyl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-(1H-pyrazol-4-yl)pyrimidin-4-amine 
• 1428253-12-6 tert-butyl 4-(4-amino-6-(4-(4-(4-fluoro-3-methylphenyl)-1-(2-((methylsulfonyl)oxy)ethyl)-1H-imidazol-2-yl)piperidin-1-yl)pyrimidin-5-yl)-1H-pyrazole-1-carboxylate 
• 1446104-05-7 2-(2-(1-(6-amino-5-bromopyrimidin-4-yl)piperidin-4-yl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-1-yl)ethanol 
• 1428250-28-5 2-(2-(1-(6-amino-5-(1H-pyrazol-4-yl)pyrimidin-4-yl)piperidin-4-yl)-4-(4-fluoro-3-methylphenyl)-1H-imidazol-1-yl)ethanol 

Relevant articles and documents

TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS

The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.

NOVEL IMIDAZOLE AMINES AS MODULATORS OF KINASE ACTIVITY

The invention provides novel imidazole amine compounds according to Formula (I) and Formula (II) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.

SEROTONIN 5-HT2B RECEPTOR INHIBITORS

Disclosed are Serotonin 5-HT2B receptor inhibitors of the formula I. Also disclosed are methods of making and methods of using these compounds