1428255-41-7

Upstream product

• 6232-88-8 4-bromomethylbenzoic Acid 
• 174137-97-4 1,4-bis(tert-butoxycarbonylmethyl)-1,4,7-triazacyclononane 
• 1428255-43-9 4-(bromomethyl)benzoic acid 9-fluorenylmethyl ester 

Downstream Products

• 1428255-45-1 C₁₈H₂₃N₃O₆^(2-)*Mn⁽²⁺⁾ 

Relevant academic research and scientific papers

IMPROVED METHODS OF IMAGING WITH Ga-68 LABELED MOLECULES

The present application discloses compositions and methods of use of 68Ga labeled molecules. Preferably, the 68Ga is attached to a peptide targetable construct and is used in a pretargeting technique with a bispecific antibody (bsAb). The bsAb comprises at least one binding site for a disease-associated antigen, such as a tumor-associated antigen, and at least one binding site for a hapten on the targetable construct. Exemplary haptens include In-DTPA and HSG. More preferably, the bsAb is administered about 24-30 hours before the targetable construct, and detection by PET imaging occurs about 1-2 hours after the targetable construct is administered. The methods and compositions are suitable for detection, diagnosis and/or imaging of various diseases, such as cancer or infectious disease.

Thermodynamic stability and relaxation studies of small, triaza-macrocyclic Mn(ii) chelates

Due to its favorable relaxometric properties, Mn2+ is an appealing metal ion for magnetic resonance imaging (MRI) contrast agents. This paper reports the synthesis and characterization of three new triazadicarboxylate-type ligands and their Mn