1428318-58-4Relevant articles and documents
Radiosynthesis of 5-[18f]fluoro-1,2,3-triazoles through aqueous iodine–[18f]fluorine exchange reaction
Abdelwahed, Sameh,Basuli, Falguni,Begley, Tadhg,Swenson, Rolf,Zhang, Xiang
, (2021/09/18)
In this report, a simple and efficient process to achieve fluorine-18-labeled 1,2,3-triazole is reported. The heteroaromatic radiofluorination was successfully achieved through an iodine– fluorine-18 exchange in an aqueous medium requiring only trace amou
Synthesis of 5-Fluorotriazoles by Silver-Mediated Fluorination of 5-Iodotriazoles
Wang, Damin,Sun, Wenjing,Chu, Taiwei
, p. 4114 - 4118 (2015/06/30)
A simple method was developed for the direct fluorination of 5-iodotriazoles with AgF as fluoride source and N1,N1,N2,N2-tetramethylethane-1,2-diamine (TMEDA) as ligand. This method is compatible with various fu
Halogen exchange (Halex) reaction of 5-iodo-1,2,3-triazoles: Synthesis and applications of 5-fluorotriazoles
Worrell, Brady T.,Hein, Jason E.,Fokin, Valery V.
, p. 11791 - 11794 (2013/01/15)
A good exchange: 5-Iodo-1,2,3-triazoles undergo facile substitution reactions with fluoride salts, thus providing ready access to 5-fluorotriazoles (see scheme). The latter can be further elaborated with various nucleophiles to furnish fully substituted 1,2,3-triazole compounds. Copyright