1428333-35-0

Basic information

• Product Name: ethyl 2-(4-methoxyphenyl)-3-(4-nitrophenyl)propanoate
• Synonyms: ethyl 2-(4-methoxyphenyl)-3-(4-nitrophenyl)propanoate
• CAS NO: 1428333-35-0
• Molecular Weight: 329.353
• Mol File: 1428333-35-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-methoxyphenyl)-3-(4-nitrophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-methoxyphenyl)-3-(4-nitrophenyl)propanoate(1428333-35-0)
• EPA Substance Registry System: ethyl 2-(4-methoxyphenyl)-3-(4-nitrophenyl)propanoate(1428333-35-0)

Safety Data

• Hazardous Substances Data: 1428333-35-0(Hazardous Substances Data)

Upstream product

• 14062-18-1 ethyl p-methoxyphenylacetate 
• 100-11-8 1-bromomethyl-4-nitro-benzene 

Downstream Products

• 400648-60-4 ethyl 2-(3-amino-4-methoxyphenyl)-3-(4-nitrophenyl)propanoate 

Relevant articles and documents

Electrochemical C-H amination: Synthesis of aromatic primary amines via N -arylpyridinium ions

We have developed a new method for C-H amination of aromatic compounds based on electrochemical oxidation of aromatic compounds in the presence of pyridine followed by the reaction of the resulting N-arylpyridinium ions with an alkylamine. This new transformation serves as a powerful method for synthesizing aromatic primary amines from aromatic compounds without using metal catalysts and harsh chemical reagents. High chemoselectivity of the present method is demonstrated by C-H amination of aromatic compounds bearing a nitro group to give a key intermediate for the synthesis of VLA-4 antagonist.