1428573-73-2

Upstream product

• 882529-68-2 (Z)-tert-butyl 3-oxo-2,3,6,7-tetrahydro-1H-azepine-1-carboxylate 
• 105-13-5 4-Methoxybenzyl alcohol 
• 1428573-72-1 tert butyl 5-(4-methoxybenzyloxy)-3-oxoazepane-1-carboxylate 

Downstream Products

• 1428573-71-0 tert butyl 3-fluoro-5-(4-methoxybenzyloxy)azepane-1-carboxylate 
• 1428573-74-3 3-fluoro-5-(4-methoxybenzyloxy)-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepane 

Relevant academic research and scientific papers

PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE

Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is thiazolyl, pyrazinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.