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CAS

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1428627-08-0

5-(4-chloro-2-methoxyphenoxy)thiophene-2-carboxaldehyde is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1428627-08-0 Structure

  • Basic information

    1. Product Name: 5-(4-chloro-2-methoxyphenoxy)thiophene-2-carboxaldehyde
    2. Synonyms: 5-(4-chloro-2-methoxyphenoxy)thiophene-2-carboxaldehyde
    3. CAS NO:1428627-08-0
    4. Molecular Formula:
    5. Molecular Weight: 268.721
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1428627-08-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(4-chloro-2-methoxyphenoxy)thiophene-2-carboxaldehyde(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(4-chloro-2-methoxyphenoxy)thiophene-2-carboxaldehyde(1428627-08-0)
    11. EPA Substance Registry System: 5-(4-chloro-2-methoxyphenoxy)thiophene-2-carboxaldehyde(1428627-08-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1428627-08-0(Hazardous Substances Data)

1428627-08-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1428627-08-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,8,6,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1428627-08:
(9*1)+(8*4)+(7*2)+(6*8)+(5*6)+(4*2)+(3*7)+(2*0)+(1*8)=170
170 % 10 = 0
So 1428627-08-0 is a valid CAS Registry Number.

1428627-08-0Relevant articles and documents

Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase

Cheng, Gang,Muench, Stephen P.,Zhou, Ying,Afanador, Gustavo A.,Mui, Ernest J.,Fomovska, Alina,Lai, Bo Shiun,Prigge, Sean T.,Woods, Stuart,Roberts, Craig W.,Hickman, Mark R.,Lee, Patty J.,Leed, Susan E.,Auschwitz, Jennifer M.,Rice, David W.,McLeod, Rima

, p. 2035 - 2043 (2013)

Triclosan is a potent inhibitor of Toxoplasma gondii enoyl reductase (TgENR), which is an essential enzyme for parasite survival. In view of triclosan's poor druggability, which limits its therapeutic use, a new set of B-ring modified analogs were designed to optimize its physico-chemical properties. These derivatives were synthesized and evaluated by in vitro assay and TgENR enzyme assay. Some analogs display improved solubility, permeability and a comparable MIC50 value to that of triclosan. Modeling of these inhibitors revealed the same overall binding mode with the enzyme as triclosan, but the B-ring modifications have additional interactions with the strongly conserved Asn130.

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