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1428653-82-0

(E)-4-(7-(4-(dimethylamino)benzylidene)-2-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-3-yl)-N,N-dimethylaniline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1428653-82-0 Structure

  • Basic information

    1. Product Name: (E)-4-(7-(4-(dimethylamino)benzylidene)-2-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-3-yl)-N,N-dimethylaniline
    2. Synonyms:
    3. CAS NO:1428653-82-0
    4. Molecular Formula:
    5. Molecular Weight: 450.627
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1428653-82-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (E)-4-(7-(4-(dimethylamino)benzylidene)-2-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-3-yl)-N,N-dimethylaniline(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E)-4-(7-(4-(dimethylamino)benzylidene)-2-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-3-yl)-N,N-dimethylaniline(1428653-82-0)
    11. EPA Substance Registry System: (E)-4-(7-(4-(dimethylamino)benzylidene)-2-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazol-3-yl)-N,N-dimethylaniline(1428653-82-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1428653-82-0(Hazardous Substances Data)

1428653-82-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1428653-82-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,8,6,5 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1428653-82:
(9*1)+(8*4)+(7*2)+(6*8)+(5*6)+(4*5)+(3*3)+(2*8)+(1*2)=180
180 % 10 = 0
So 1428653-82-0 is a valid CAS Registry Number.

1428653-82-0Downstream Products

1428653-82-0Relevant articles and documents

Synthesis, molecular docking and in vitro antimicrobial studies of new hexahydroindazole derivatives of curcumin

Kumar, Dileep,Harish,Gangwar, Mayank,Kumar, Manish,Kumar, Dharmendra,Tilak, Ragini,Nath, Gopal,Kumar, Ashok,Singh, Sushil Kumar

, p. 119 - 128 (2013)

A series of hexahydroindazole analogues of curcumin were synthesized and investigated for in vitro and in silico antimicrobial activity. The structures of synthesized compounds were identified on the basis of satisfactory analytical and spectral data (1H NMR, 13C NMR, EI-MASS techniques and elemental analysis). Synthesized compounds showed moderate to high activity against both bacterial and fungal strains. All compounds were docked computationally to the active site of enzyme L-glutamine: D-fructose-6-phosphate amido-transferase [GlcN-6-P] (EC 2.6.1.16). The autodock programme 4.0 was employed to perform automated molecular docking. (E)-1-(7-(3-methoxybenzylidene) -3-(3- methoxyphenyl)-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl)ethanone (A7) turned out to be the most potent analogue of the series, showing best activity against bacterial and fungal strains. Compound A7 showed minimum binding and docking energy and may be considered as good inhibitor of GlcN-6-P synthase. Further investigation and optimization of this lead could provide new antimicrobial molecules.

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