1428668-17-0

Basic information

• Product Name: methyl 3-amino-4-[2-(1-cyclohexenyl)ethyl]aminobenzoate
• Synonyms: methyl 3-amino-4-[2-(1-cyclohexenyl)ethyl]aminobenzoate
• CAS NO: 1428668-17-0
• Molecular Weight: 274.363
• Mol File: 1428668-17-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: methyl 3-amino-4-[2-(1-cyclohexenyl)ethyl]aminobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-amino-4-[2-(1-cyclohexenyl)ethyl]aminobenzoate(1428668-17-0)
• EPA Substance Registry System: methyl 3-amino-4-[2-(1-cyclohexenyl)ethyl]aminobenzoate(1428668-17-0)

Safety Data

• Hazardous Substances Data: 1428668-17-0(Hazardous Substances Data)

Upstream product

• 3399-73-3 2-(1-cyclohexenyl)ethylamine 
• 1430101-77-1 methyl 4-[2-(1-cyclohexenyl)ethyl]amino-3-nitrobenzoate 
• 453-71-4 3-nitro-4-fluorobenzoic acid 
• 329-59-9 4-fluoro-3-nitro-benzoic acid methyl ester 

Downstream Products

• 1430101-79-3 methyl 3-[(2-amino-3-pyridyl)carbonyl]amino-4-[2-(1-cyclohexenyl)ethyl]aminobenzoate 
• 1430101-83-9 methyl 2-(2-amino-3-pyridyl)-1-[2-(1-cyclohexenyl)ethyl]-1H-benzo[d]imidazole-5-carboxylate 
• 1430101-57-7 methyl 2-[3-(tert-butylamino)-2-(4-nitrophenyl)imidazo[1,2-a]pyridin-8-yl]-1-[2-(1-cyclohexenyl)ethyl]-1H-benzo[d]imidazole-5-carboxylate 
• 1430101-58-8 methyl 2-[3-(tert-butylamino)-2-phenylimidazo[1,2-a]pyridin-8-yl]-1-[2-(1-cyclohexenyl)ethyl]-1H-benzo[d]imidazole-5-carboxylate 
• 1430101-59-9 methyl 2-[2-(1,3-benzodioxol-5-yl)-3-(tert-butylamino)imidazo[1,2-a]pyridin-8-yl]-1-[2-(1-cyclohexenyl)ethyl]-1H-benzo[d]imidazole-5-carboxylate 

Relevant articles and documents

NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS

The present invention provides novel substituted benzimidazole derivatives used as DAAO inhibitors and for treatment and/or prevention of neurological disorders.

A Novel Mechanistic Study on Ultrasound-Assisted, One-Pot Synthesis of Functionalized Benzimidazo[2,1-b]quinazolin-1(1H)-ones

Ultrasound-assisted synthesis of benzimidazo[2,1-b]quinazolin-1(1H)-ones was achieved via piperidine-catalyzed three-component reaction of 2-aminobenzimidazoles, an aromatic aldehyde, and 1,3-dione in aqueous isopropanol. This mechanism was first suspected following our identification of unusual reaction intermediates in a one-pot reaction. An unprecedented coupling reaction, it involved a nucleophilic attack by 2-aminobenzimidazole on in situ generated Michael adduct, followed by electrocyclic ring formation reaction. In contrast to the commonly accepted mechanism, that the direct reaction of 2-amino benzimidazole with a Knoevenagel adduct cannot deliver target compounds.

Three Component Divergent Reactions: Base-Controlled Amphiphilic Synthesis of Benzimidazole-Linked Thiazetidines and Fused Thiadiazines

A divergent reaction of 2-aminobenzimidazole with isothiocyanates and dihalomethanes has been developed for the selective synthesis of benzoimidazothiazetidine and benzoimidazothiadiazine. A single-pot reaction of 2-aminobenzimidazole in the presence of s