142867-56-9Relevant academic research and scientific papers
Prodrugs of Nitroxyl as Inhibitors of Aldehyde Dehydrogenase
Lee, Melinda J. C.,Nagasawa, Herbert T.,Elberling, James A.,DeMaster, Eugene G.
, p. 3648 - 3652 (2007/10/02)
In the preceding paper, analogs of chlorpropamide with an OMe substituent on the sulfonamide nitrogen were shown to inhibit aldehyde dehydrogenase (AlDH), and it was postulated that these compounds were bioactivated by O-demethylation to release nitroxyl
