1428883-53-7Relevant academic research and scientific papers
Facile syntheses of substituted, conformationally-constrained benzoxazocines and benzazocines via sequential multicomponent assembly and cyclization
Sahn, James J.,Martin, Stephen F.
scheme or table, p. 6855 - 6858 (2012/02/05)
A multicomponent assembly process (MCAP) was utilized to prepare versatile intermediates that are suitably functionalized for subsequent cyclizations via Ullmann and Heck reactions to efficiently construct substituted 2,6-methanobenzo[b][1,5]oxazocines an
Ring-closing metathesis and ring-closing metathesis-isomerisation approach to 1-phosphonylated 2-benzazocines
Dieltiens, Nicolai,Stevens, Christian V.,Masschelein, Kurt,Hennebel, Geert,Van der Jeught, Sarah
, p. 4295 - 4303 (2008/09/19)
An RCM strategy has been developed for the synthesis of phosphonylated benzazocines and their corresponding isomerised analogues. The aminophosphonate precursors were obtained by a one-pot three-component condensation in moderate yield.
