142896-65-9Relevant academic research and scientific papers
Fluoronaphthyridines as Antibacterial Agents. 6. Synthesis and Structure-Activity Relationships of New Chiral 7-(1-, 3-, 4-, and 6-Methyl-2,5-diazabicycloheptan-2-yl)naphthyridine Analogues of 7-heptan-2-yl>-1-(1,1-d
Remuzon, Philippe,Bouzard, Daniel,Guiol, Chantal,Jacquet, Jean-Pierre
, p. 2898 - 2909 (2007/10/02)
A series of novel chiral 7-(1-, 3-, 4-, and 6-methylheptan-2-yl>-substituted naphthyridines has been prepared with the aim of obtaining good in vitro and in vivo antibacterial agents with a decrease of the pseudoallergic t
PREPARATION OF (6R)- AND (6S)-(1R,4R)-6-METHYL-2-(p-TOLUENESULFONYL)-5-PHENYLMETHYL-2,5-DIAZABICYCLOHEPTANES, INTERMEDIATES IN A SYNTHESIS OF NEW QUINOLONES
Remuzon, Philippe,Bouzard, Daniel,Dussy, Christian,Jacquet, Jean-Pierre,Massoudi, Massoud
, p. 241 - 245 (2007/10/02)
An efficjent chiral synthesis of both diastereoisomers (2a) and (2b) was preformed using trans-4-hydroxy-L-proline as starting material.These bridged piperazines were used in the preparation of quinolones.
