116143-06-7Relevant articles and documents
FUSED PYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
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Page/Page column 35, (2009/12/05)
Novel[1.2.4]triazolo[1,5-a]pyrazine and imidazo[1,2-a]pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, and others.
Azadideoxyadenosine: Synthesis, enzymology, and anti-HIV activity
Nishonov, Abdumalik A.,Ma, Xiaohui,Nair, Vasu
, p. 4099 - 4101 (2007/10/03)
Synthesis of an azanucleoside, a new analogue of dideoxyadenosine, is described. This compound is only slowly deaminated by mammalian adenosine deaminase and it is a substrate for adenosine kinase. It exhibits in vitro anti-HIV activity.
Fluoronaphthyridines and Quinolones as Antibacterial Agents. 2. Synthesis and Structure-Activity Relationships of New 1-tert-Butyl 7-Substituted Derivatives
Bouzard, D.,Di Cesare, P.,Essiz, M.,Jacquet, J. P.,Kiechel, J. R.,et al.
, p. 1344 - 1352 (2007/10/02)
A number of 7-substituted-1-tert-butyl-6-fluoroquinolone-3-carboxylic acids and 7-substituted-1-tert-butyl-6-fluoro-1,8-naphthyridine-3-carboxylic acids have been prepared and tested for antibacterial activities.Among those the 7-aminopyrrolidinyl 20b and