1429057-66-8

Basic information

• Product Name: C₅₁H₄₅N₅O₅
• CAS NO: 1429057-66-8
• Molecular Weight: 807.949
• Mol File: 1429057-66-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₁H₄₅N₅O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₁H₄₅N₅O₅(1429057-66-8)
• EPA Substance Registry System: C₅₁H₄₅N₅O₅(1429057-66-8)

Safety Data

• Hazardous Substances Data: 1429057-66-8(Hazardous Substances Data)

Upstream product

• 1429057-59-9 C₂₇H₂₂N₄O₃ 
• 13752-40-4 9-ethynylanthracene 
• 166247-63-8 7-deaza-2'-deoxy-7-iodoadenosine 
• 1429057-64-6 C₃₀H₂₇N₅O₃ 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 1429057-68-0 C₆₀H₆₂N₇O₆P 

Relevant articles and documents

Synthesis of solvatofluorochromic 7-arylethynylated 7-deaza-2′- deoxyadenosine derivatives: Application to the design of environmentally sensitive fluorescent probes forming stable DNA duplexes

We synthesized environmentally sensitive fluorescent (ESF) 7-deaza-2′-deoxyadenosine derivatives including ethynylanthracene substituted atzA (1) and ethynylnaphthalene substituted nzA (2a), cnzA (2b), anzA (2c), and dnzA (2d), and investigated their photophysical properties. Among them, only push-pull type cyano- and acetyl-substituted naphthylethynylated 7-deaza-2′-deoxyadenosine, cnzA (2b) and anzA (2c), exhibited remarkable solvatofluorochromic properties (Δλ = 71 and 63 nm, respectively). We incorporated non-solvatofluorochromic atzA (1) and solvatofluorochromic cnzA (2b) into oligodeoxynucleotides and found that cnzA (2b) forms a stable base pair with both thymine and cytosine, being accompanied by a change of fluorescence intensity. Such ESF nucleosides can be used for studying structures and functions of nucleic acids.