1429171-63-0

Basic information

• Product Name: 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (1-benzyl-4-methylpiperidin-4-yl)amide
• Synonyms: 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (1-benzyl-4-methylpiperidin-4-yl)amide
• CAS NO: 1429171-63-0
• Molecular Weight: 539.677
• Mol File: 1429171-63-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (1-benzyl-4-methylpiperidin-4-yl)amide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (1-benzyl-4-methylpiperidin-4-yl)amide(1429171-63-0)
• EPA Substance Registry System: 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (1-benzyl-4-methylpiperidin-4-yl)amide(1429171-63-0)

Safety Data

• Hazardous Substances Data: 1429171-63-0(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 1429171-61-8 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid methyl ester 
• 163271-06-5 4-amino-1-benzyl-4-methylpiperidine 
• 1429171-62-9 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid 
• 1429171-60-7 6-(4-hydroxyphenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid methyl ester 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 1429171-64-1 6-(4-hydroxyphenyl)-3-methyl-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (4-methylpiperidin-4-yl)-amide 

Relevant articles and documents

6-(4-Hydroxy-phenyl)-3-alkyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula I, in which R1, R2, R3, R4, R5, R6 and R7 are defined as indicated below. The compounds of the formula I are kinase inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.