163271-06-5Relevant articles and documents
Radiosynthesis and Biological Evaluation of [18F]R91150, a Selective 5-HT2AReceptor Antagonist for PET-Imaging
Willmann, Michael,Hegger, Julian,Neumaier, Bernd,Ermert, Johannes
, p. 738 - 744 (2021/05/04)
Serotonergic 5-HT2A receptors in cortical and forebrain regions are an important substrate for the neuromodulatory actions of serotonin in the brain. They have been implicated in the etiology of many neuropsychiatric disorders and serve as a target for an
COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE
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, (2008/12/04)
Compounds of formula (I) or a salt thereof are provided: (I) wherein R4, R5, R6, Q and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic
CHEMICAL COMPOUNDS
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Page/Page column 74-75, (2008/06/13)
The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5, m and n are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.