14294-09-8

Basic information

• Product Name: 1-PIPERIDINETHIOCARBOXAMIDE
• Synonyms: PIPERIDINE-1-CARBOTHIOIC ACID AMIDE;1-PIPERIDINETHIOCARBOXAMIDE;1-PIPERIDINETHIOCARBOXIMIDE;1-Piperidinecarbothioamide;Piperidine-1-thiocarboxamide, 98%;1-PIPERIDINETHIOCARBOXAMIDE(I)
• CAS NO: 14294-09-8
• Molecular Formula: C₆H₁₂N₂S
• Molecular Weight: 144.24
• Mol File: 14294-09-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 128-130°C
• Boiling Point: 237.3 °C at 760 mmHg
• Flash Point: 97.3 °C
• Appearance: /
• Density: 1.165 g/cm³
• Vapor Pressure: 0.0451mmHg at 25°C
• Refractive Index: 1.593
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 16.34±0.20(Predicted)
• BRN: 383640
• CAS DataBase Reference: 1-PIPERIDINETHIOCARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PIPERIDINETHIOCARBOXAMIDE(14294-09-8)
• EPA Substance Registry System: 1-PIPERIDINETHIOCARBOXAMIDE(14294-09-8)

Safety Data

• Hazard Codes: T
• Statements: 20/22-25
• Safety Statements: 22-36/37-45
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 14294-09-8(Hazardous Substances Data)

Usage

General Description

1-Piperidinethiocarboxamide, also known as thiram, is a chemical that is commonly used as a fungicide and pesticide. It is a white to light yellow solid that is insoluble in water and has a pungent odor. Thiram is often used to protect crops such as fruits, vegetables, and ornamental plants from various fungal diseases, and it is also used as a seed treatment to protect seeds from fungal infections. Additionally, thiram has been used in rubber production as an accelerator and in the production of dyes and other chemical processes. However, it is important to note that thiram is toxic to humans and animals and can cause irritation to the skin, eyes, and respiratory system, as well as more serious health effects with prolonged or high-level exposure. Therefore, it is important to handle and use thiram with caution and in accordance with safety guidelines.

InChI:InChI=1/C6H12N2S/c7-6(9)8-4-2-1-3-5-8/h1-5H2,(H2,7,9)

Upstream product

• 40398-27-4 (piperidine-1-thiocarbonyl)-carbamic acid ethyl ester 
• 110-89-4 piperidine 
• 540-72-7 sodium thiocyanide 
• 7732-18-5 water 
• 68-12-2 N,N-dimethyl-formamide 
• 556-61-6 methyl thioisocyanate 
• 1530-87-6 1-piperidinylcarbonnitrile 
• 74734-11-5 1H-imidazole-1-carbodithioic acid methyl ester 
• 625-57-0 O-ethyl thiocarbamate 

Downstream Products

• 4175-70-6 2-(piperidin-1-yl)thiazole 

Relevant articles and documents

Selenoureas and thioureas are effective superoxide radical scavengers in vitro

Oxygen radicals, such as superoxide radicals, embellishing DNA, protein, lipids, etc., and carrying out the obstacle of the function of a cell is known. It depends for the oxidant level in the living body on the balance of a generation system and an elimination system of oxygen radicals, and research which controls an oxidant level in the living body is briskly done by taking in the substance which eliminates an oxygen radical. We investigated scavenging effects of superoxide radicals by selenoureas and thioureas using a highly sensitive and quantitative chemiluminescence method. At 330 nM, five selenoureas and five thioureas scavenged fractions of superoxide radicals (O 2-) ranging from 8.4% to 87.6%. Among five N,N-unsubstituted selenoureas and N,N-unsubstituted thioureas 1-selenocarbamoylpiperidine and 1-thiocarbamoylpyrrolidine were the most effective scavengers. A possibility that selenoureas could use it as a new superoxide anion-scavenging substance from the result of this research became clear.

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Crystal structures and antimicrobial activities of copper(II) complexes of fluorine-containing thioureido ligands

Cu(II) complexes with N-4-fluorobenzoylpiperidine-1-carbothioimidate (L1), N-2-fluorobenzoylpiperi-dine-1-carbothioimidate (L2) and 2-fluorobenzoate (L3) have been synthesized and characterized by elemental analysis, Fourier Transform infrared (FT-IR), Ul