4175-70-6

Basic information

• Product Name: 1-(1,3-THIAZOL-2-YL)PIPERIDINE
• Synonyms: 1-(1,3-THIAZOL-2-YL)PIPERIDINE;2-Piperidinothiazole;1-(2-Thiazolyl)piperidine;2-(Piperidin-1-yl)thiazole
• CAS NO: 4175-70-6
• Molecular Formula: C8H12N2S
• Molecular Weight: 168.26
• Mol File: 4175-70-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 270℃
• Flash Point: 117℃
• Appearance: /
• Density: 1.165
• PKA: 6.45±0.10(Predicted)
• CAS DataBase Reference: 1-(1,3-THIAZOL-2-YL)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,3-THIAZOL-2-YL)PIPERIDINE(4175-70-6)
• EPA Substance Registry System: 1-(1,3-THIAZOL-2-YL)PIPERIDINE(4175-70-6)

Safety Data

• Hazardous Substances Data: 4175-70-6(Hazardous Substances Data)

Usage

General Description

1-(1,3-thiazol-2-yl)piperidine is a chemical compound with the molecular formula C9H14N2S. It is a piperidine derivative with a thiazole ring attached to the nitrogen atom. 1-(1,3-THIAZOL-2-YL)PIPERIDINE is commonly used in the pharmaceutical industry as a building block for the synthesis of various bioactive molecules and drugs. 1-(1,3-thiazol-2-yl)piperidine has been studied for its potential therapeutic applications, including as an antipsychotic, antihistaminic, and anticonvulsant agent. Its unique structure and pharmacological properties make it a valuable compound in drug discovery and development.

Upstream product

• 110-89-4 piperidine 
• 3034-52-4 2-chlorothiazole 
• 1606-76-4 2-nitrothiazole 
• 14294-09-8 piperidine-1-carbothioamide 
• 3034-53-5 2-bromo-1,3-thiazole 

Downstream Products

• 477868-70-5 2-((2-(piperidin-1-yl)thiazol-5-yl)methylene)malononitrile 
• 129865-52-7 2-(piperidin-1-yl)thiazole-5-carbaldehyde 

Relevant articles and documents

-

-

Pd-PEPPSI-IPentAn Promoted Deactivated Amination of Aryl Chlorides with Amines under Aerobic Conditions

We report herein a highly efficient Pd-catalyzed amination by "bulky-yet-flexible" Pd-PEPPSI-IPentAn complexes. The relationship between the N-heterocyclic carbenes (NHCs) structure and catalytic properties was discussed. Sterically hindered (hetero)aryl chlorides and a variety of aliphatic and aromatic amines can be applied in this cross-coupling, which smoothly proceeded to provide desired products. The operationally simple protocol highlights the rapid access to CAr-N bond formation under mild conditions without the exclusion of air and moisture.

Synthesis and Characterization of 1,3-Bis-(2-dialkylamino-5-thiazolyl)-Substituted Squaraines and Their 2-(Dialkylamino)thiazole Precursors

By condensation of squaric acid (1) with 2-(dialkylamino)-substituted thiazoles 8 a novel type of heterocyclic-substituted squaraines of the general structure 9 was prepared in moderate yield mostly.The squaraines 9 obtained are sparingly soluble in the most organic solvents and exhibit, in these solvents, narrow absorption bands in the visible range at about 620-700 nm.In dispersed form, the absorption bands of the squaraines 9 are, however, broadened and shifted into the NIR region at about 900 nm.These unique properties of the new squaraines 9 suggest the use of these dyes as spectral sensitizers for laser-driven data recording or data storage media. - Key Words: Squaraines/ Squaric acid/ Thiazoles/ Sensitizers