1429427-68-8

Basic information

• Product Name: (E)-4-(4-isopropylphenyl)-4-oxo-2-butenoic acid (3,5-dimethoxyphenyl)amide
• CAS NO: 1429427-68-8
• Molecular Weight: 353.418
• Mol File: 1429427-68-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-4-(4-isopropylphenyl)-4-oxo-2-butenoic acid (3,5-dimethoxyphenyl)amide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(4-isopropylphenyl)-4-oxo-2-butenoic acid (3,5-dimethoxyphenyl)amide(1429427-68-8)
• EPA Substance Registry System: (E)-4-(4-isopropylphenyl)-4-oxo-2-butenoic acid (3,5-dimethoxyphenyl)amide(1429427-68-8)

Safety Data

• Hazardous Substances Data: 1429427-68-8(Hazardous Substances Data)

Upstream product

• 29587-82-4 (E)-4-(4-isopropylphenyl)-4-oxo-2-butenoic acid 
• 10272-07-8 3.5-dimethoxyaniline 
• 98-82-8 Isopropylbenzene 

Downstream Products

• 1615217-32-7 N-(3,5-dimethoxyphenyl)-4-(4-isopropylphenyl)-4-oxo-2-(1-piperidinyl)butanamide 
• 1615217-33-8 N-(3,5-dimethoxyphenyl)-4-(4-isopropylphenyl)-4-oxo-2-(1-imidazolyl)butanamide 
• 1615217-34-9 N-(3,5-dimethoxyphenyl)-4-(4-isopropylphenyl)-4-oxo-2-(4-morpholinyl)butanamide 
• 1615217-35-0 N-(3,5-dimethoxyphenyl)-4-(4-isopropylphenyl)-4-oxo-2-[1-(4-methylpiperazinyl)]butanamide 
• 1615217-69-0 N-(3,5-dimethoxyphenyl)-2-[4-(2-dimethylaminoethyl)-1-piperazinyl]-4-(4-isopropylphenyl)-4-oxobutanamide 

Relevant articles and documents

Structural modifications of 4-aryl-4-oxo-2-aminylbutanamides and their acetyl- and butyrylcholinesterase inhibitory activity. Investigation of AChE-ligand interactions by docking calculations and molecular dynamics simulations

Congeneric set of thirty-eight 4-aryl-4-oxo-2-(N-aryl/cycloalkyl) butanamides has been designed, synthesized and evaluated for acetyl- and butyrylcholinesterase inhibitory activity. Structural variations included cycloalkylamino group attached to C2 posit