142952-69-0Relevant articles and documents
Synthesis and testing of new modified nucleosides
Jung, Michael E.,Nichols, Christopher J.,Kretschik, Oliver,Xu, Yue
, p. 541 - 546 (2007/10/03)
New efficient routes for the high-yielding synthesis of several classes of modified nucleosides have been developed. We have prepared both the D- and L-enantiomers of the methylene-expanded oxetanocin isonucleosides 1a-c and the L-2',3'-dideoxy isonucleosides 2abc (both the oxa and thia analogues) as well as new routes for the preparation of L-ribose and 2-deoxy L-ribose 3ab and their modified nucleosides 4.
Enantiospecific Synthesis of 3'-Hetero-dideoxy Nucleoside Analogues as Potential Anti-HIV Agents
Jones, Martin F.,Noble, Stewart A.,Robertson, Colin A.,Storer, Richard,Highcock, Rona M.,Lamont, R. Brian
, p. 1427 - 1436 (2007/10/02)
Two series of analogues of 2',3'-dideoxy carbocyclic nucleosides, in which the 3'-carbon atom is replaced by either an oxygen or a sulfur atom, have been prepared enantiospecifically from diacetone-L-glucose and diacetone-D-glucose respectively.Within eac