1429637-84-2

Upstream product

• 615-93-0 2,5-Dichloro-1,4-benzoquinone 
• 146631-00-7 [4-(benzyloxy)phenyl]boronic acid 
• 583-78-8 2,5-dichlorophenol 

Downstream Products

• 1429637-86-4 4-(benzo[d][1,3]dioxol-5-yl)-4’-(benzyloxy)-3,6-dimethoxy-[1,1’-biphenyl]-2,5-dione 
• 1429637-87-5 4-(benzo[d][1,3]dioxol-5-yl)-4’-(benzyloxy)-[1,1’-biphenyl]-2,3,5,6-tetrayl tetraacetate 
• 1429637-88-6 4’’-(benzyloxy)-3,4-dihydroxy-[1,1’:4’,1’’-terphenyl]-2’,3’,5’,6’-tetrayl tetraacetate 
• 1429637-89-7 4’’-(benzyloxy)-3,4-dioxo-3,4-dihydro-[1,1’:4’,1’’-terphenyl]-2’,3’,5’,6’-tetrayl tetraacetate 
• 1429637-90-0 C₄₆H₄₈N₂O₁₅ 
• 1429637-91-1 C₄₆H₄₈N₂O₁₅ 
• 1429637-92-2 C₄₆H₄₈N₂O₁₅ 
• 1429637-93-3 C₄₆H₄₈N₂O₁₅ 
• 1429637-85-3 4’-(benzyloxy)-3,6-dimethoxy-[1,1’-biphenyl]-2,5-dione 
• 1110631-68-9 4’-(benzyloxy)-4-bromo-3,6-dimethoxy-[1,1’-biphenyl]-2,5-dione 

Relevant academic research and scientific papers

Generation of arylated quinones by iron-catalyzed oxidative arylation of phenols: Formal synthesis of phellodonin, sarcodonin ε, leucomelone and betulinan A

Biologically and pharmaceutically relevant arylated quinones (Quin-Ar) have been synthesized via direct C-H arylation of a variety of phenols using arylboronic acids. An inexpensive, environmentally friendly iron catalyst, ferric sulphate, Fe2(SO4)3, was employed in this operationally simple and efficient method.

Convergent synthesis and structural confirmation of phellodonin and Sarcodonin ε

The first synthesis of members of the sarcodonin family, phellodonin and sarcodonin ε, is reported herein. This verifies that the unprecedented and seemingly unstable N,N-dioxide-containing benzodioxazine framework can be constructed in the laboratory and lends further support to the proposed structures. The key step in the synthesis involves a biomimetic hetero-Diels-Alder reaction between a pyrazine N-oxide and an ortho-quinone.