1429637-92-2Relevant academic research and scientific papers
Convergent synthesis and structural confirmation of phellodonin and Sarcodonin ε
Usui, Ippei,Lin, David W.,Masuda, Takeshi,Baran, Phil S.
, p. 2080 - 2083 (2013/06/04)
The first synthesis of members of the sarcodonin family, phellodonin and sarcodonin ε, is reported herein. This verifies that the unprecedented and seemingly unstable N,N-dioxide-containing benzodioxazine framework can be constructed in the laboratory and lends further support to the proposed structures. The key step in the synthesis involves a biomimetic hetero-Diels-Alder reaction between a pyrazine N-oxide and an ortho-quinone.
