1429908-35-9

Usage

Uses

Used in Pharmaceutical Research:
1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]Piperazine is used as a starting material for the synthesis of various organic compounds in pharmaceutical research. Its versatile chemical structure allows for the creation of new compounds with potential therapeutic effects.
Used in Drug Development:
In the drug development industry, 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]Piperazine is utilized as a valuable building block. Its incorporation into the molecular structures of new drugs aids in the discovery and design of pharmaceutical products with improved efficacy and safety profiles.
Used in Biological Activity Studies:
1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]Piperazine is also used in biological activity studies to explore its potential therapeutic effects. Researchers are investigating its interactions with biological systems to understand its possible applications in treating various diseases and conditions.

Upstream product

• 508233-74-7 vortioxetine 
• 13616-82-5 2,4-dimethyl-thiophenol 
• 367-11-3 ortho-difluorobenzene 
• 110-85-0 piperazine 

Downstream Products

• 508233-74-7 vortioxetine 
• 960203-28-5 Vortioxetine hydrochloride 
• 960203-27-4 Vortioxetine hydrobromide 

Relevant academic research and scientific papers

Piperazinyl-substituted diarylsulfoxide compound as well as composition and application thereof

The invention belongs to the technical field of medicines, and particularly relates to a piperazinyl-substituted diarylsulfoxide compound as well as a composition and an application thereof. Accordingto the piperazinyl-substituted diarylsulfoxide compound, a piperazinyl-substituted diarylthioether compound is used as a raw material and is added into a mixed solution of water and acetonitrile, themixture is subjected to an oxidation reaction at room temperature, and the piperazinyl-substituted diarylsulfoxide compound is prepared; the obtained compound can generate a synergistic effect with aplum flower extract to effectively promote antibacterial and anti-tumor effects of the compound.

Preparation method and applications of vortioxetine hydrobromide degradation product

The present invention provides a preparation method of a compound represented by a formula I, and applications of the compound in detection of the related substance content in vortioxetine hydrobromide. The preparation method comprises: dissolving a compound represented by a formula II in an organic acid, adding hydrogen peroxide, carrying out a reaction for 2-20 h, and treating to obtain the compound represented by the formula I. According to the present invention, the research results of the compound show that the compound can provide the reference substance for the qualitative and quantitative analysis of the vortioxetine hydrobromide impurity so as to effectively improve the quality control standard of vortioxetine hydrobromide, and ensure the safe medication. The formulas I and II are defined in the specification.

NEW PROCESS FOR THE SYNTHESIS OF 1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE

The present invention provides a new synthetic process for the production of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine (vortioxetine), an experimental drug under development for the treatment of depression and anxiety, which comprises the reaction of a compound of formula (VII), or salt thereof, (VII) wherein Q represents S, SO or SO2 and LG represents a leaving group, with a compound of formula (XI), or salt thereof, (XI) wherein Z represents hydrogen or a protecting group. New intermediate compounds are also provided.