1429908-35-9

Basic information

• Product Name: 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine
• Synonyms: 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine;Vortioxetine Impurity 19;Vortioxetine impurity D;Vortioxetine Impurity 19 (Vortioxetine Sulfoxide)
• CAS NO: 1429908-35-9
• Molecular Formula: C18H22N2OS
• Molecular Weight: 314.44508
• EINECS: -0
• Mol File: 1429908-35-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine(1429908-35-9)
• EPA Substance Registry System: 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine(1429908-35-9)

Safety Data

• Hazardous Substances Data: 1429908-35-9(Hazardous Substances Data)

Usage

General Description

1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine is a chemical compound that belongs to the sulfinylphenylpiperazine class. It has a molecular formula of C19H24N2OS and a molecular weight of 324.47 g/mol. 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine is commonly used in pharmaceutical research as a starting material for the synthesis of various organic compounds. It exhibits potential biological activities and is being studied for its possible therapeutic effects. In addition, its structure and properties make it a valuable building block for the development of new drugs and pharmaceutical products.

Upstream product

• 110-85-0 piperazine 
• 367-11-3 ortho-difluorobenzene 
• 13616-82-5 2,4-dimethyl-thiophenol 
• 508233-74-7 vortioxetine 

Downstream Products

• 508233-74-7 vortioxetine 
• 960203-28-5 Vortioxetine hydrochloride 
• 960203-27-4 Vortioxetine hydrobromide 

Relevant articles and documents

Piperazinyl-substituted diarylsulfoxide compound as well as composition and application thereof

The invention belongs to the technical field of medicines, and particularly relates to a piperazinyl-substituted diarylsulfoxide compound as well as a composition and an application thereof. Accordingto the piperazinyl-substituted diarylsulfoxide compound, a piperazinyl-substituted diarylthioether compound is used as a raw material and is added into a mixed solution of water and acetonitrile, themixture is subjected to an oxidation reaction at room temperature, and the piperazinyl-substituted diarylsulfoxide compound is prepared; the obtained compound can generate a synergistic effect with aplum flower extract to effectively promote antibacterial and anti-tumor effects of the compound.

NEW PROCESS FOR THE SYNTHESIS OF 1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE

The present invention provides a new synthetic process for the production of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine (vortioxetine), an experimental drug under development for the treatment of depression and anxiety, which comprises the reaction of a compound of formula (VII), or salt thereof, (VII) wherein Q represents S, SO or SO2 and LG represents a leaving group, with a compound of formula (XI), or salt thereof, (XI) wherein Z represents hydrogen or a protecting group. New intermediate compounds are also provided.