142991-43-3Relevant academic research and scientific papers
Borohydride Reduction of Imidazolidinodithiadiazepines
Bodor, Nicholas,Koltai, Ernoe,Prokai, Laszlo
, p. 4767 - 4772 (1992)
Imidazolidinodithiadiazepines are converted to the ten-membered saturated heterocycles via borohydride reduction in acidic media or using ''in situ'' generated borane.Reductive alkylation in acetic or propionic acid as a solvent represents a significant side reaction.Relatively stable boron compounds are identified as intermediates which yield the saturated heterocycles upon acidic hydrolysis. Key Words: Imidazolidinodithiadiazepines; 1,2-dithia-5,8-diaza-cyclodecane; borohydride reduction; by-products; reaction mechanism
