143-06-6

Basic information

• Product Name: (6-Aminohexyl)carbamic acid
• Synonyms: (6-aminohexyl)-carbamicaci;(6-aminohexyl)carbamicacid;(6-aminohexyl)-Carbamicacid;6-aminohexylcarbamicacid;diak1;HEXAMETHYLENEDIAMINE CARBAMATE;Carbamic acid, (6-aminohexyl)-;(6-Aminohexyl)carbaminsure
• CAS NO: 143-06-6
• Molecular Formula: C₇H₁₆N₂O₂
• Molecular Weight: 160.21
• EINECS: 205-581-6
• Mol File: 143-06-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 154-158 °C
• Boiling Point: 159.19℃[at 101 325 Pa]
• Appearance: liquid
• Density: 1.06 g/cm³
• Vapor Pressure: 0.01Pa at 25℃
• Refractive Index: 1.482
• Storage Temp.: 2-8°C
• PKA: -1.41±0.12(Predicted)
• Water Solubility: 128.65g/L at 25℃
• CAS DataBase Reference: (6-Aminohexyl)carbamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (6-Aminohexyl)carbamic acid(143-06-6)
• EPA Substance Registry System: (6-Aminohexyl)carbamic acid(143-06-6)

Safety Data

• Hazardous Substances Data: 143-06-6(Hazardous Substances Data)

Usage

Flammability and Explosibility

Flammable

InChI:InChI=1/C7H16N2O2/c8-5-3-1-2-4-6-9-7(10)11/h9H,1-6,8H2,(H,10,11)

Synthetic route

1,6-Hexanediamine (124-09-4) + carbon monoxide (201230-82-2) → 1,6-diaminohexane carbamic acid (143-06-6)

Conditions	Yield
With water; tetracarbonyl nickel In toluene at 170℃; for 20h;

diazomethane (186581-53-3, 908094-01-9) + 1,6-diaminohexane carbamic acid (143-06-6) + hexanediyldiamine salt of/the/ N,N'-hexanediyl-bis-carbamic acid → methyl 6-amino-hexane-1-carbamate

Conditions	Yield
With diethyl ether

diazomethane (186581-53-3, 908094-01-9) + 1,6-diaminohexane carbamic acid (143-06-6) + hexanediyldiamine salt of/the/ N,N'-hexanediyl-bis-carbamic acid → 1,6-bis(methoxycarbonylamino)hexane (6030-54-2)

Conditions	Yield
With diethyl ether

1,6-diaminohexane carbamic acid (143-06-6) + hexanediyldiamine salt of/the/ N,N'-hexanediyl-bis-carbamic acid → N,N'-hexanediyl-bis-carbamic acid ; calcium salt

Conditions	Yield
With calcium hydroxide; water at 0℃;

Upstream product

• 124-09-4 1,6-Hexanediamine 
• 201230-82-2 carbon monoxide 
• 124-38-9 carbon dioxide 

Relevant articles and documents

CARBON DIOXIDE-REVERSIBLY-PROTECTED CHAIN EXTENSION-CROSSLINKING AGENT AND PREPARATION METHOD AND USE THEREOF

Carbon dioxide-reversibly-protected chain extension-crosslinking agents and a preparation method and use thereof are disclosed, The carbon dioxide-reversibly-protected chain extension-crosslinking agents have chemical structures represented by Formula I, Formula II, Formula III or Formula IV, wherein, n, m and p are integers, R is either OCH2CH(CH3) or OCH2CH2, 1≤n≤20, 1≤m≤10, and 1≤p≤10.