143-06-6

Usage

Flammability and Explosibility

Flammable

InChI:InChI=1/C7H16N2O2/c8-5-3-1-2-4-6-9-7(10)11/h9H,1-6,8H2,(H,10,11)

Synthetic route

1,6-Hexanediamine (124-09-4) + carbon monoxide (201230-82-2) → 1,6-diaminohexane carbamic acid (143-06-6)

Conditions	Yield
With water; tetracarbonyl nickel In toluene at 170℃; for 20h;

diazomethane (186581-53-3, 908094-01-9) + 1,6-diaminohexane carbamic acid (143-06-6) + hexanediyldiamine salt of/the/ N,N'-hexanediyl-bis-carbamic acid → methyl 6-amino-hexane-1-carbamate

Conditions	Yield
With diethyl ether

diazomethane (186581-53-3, 908094-01-9) + 1,6-diaminohexane carbamic acid (143-06-6) + hexanediyldiamine salt of/the/ N,N'-hexanediyl-bis-carbamic acid → 1,6-bis(methoxycarbonylamino)hexane (6030-54-2)

Conditions	Yield
With diethyl ether

1,6-diaminohexane carbamic acid (143-06-6) + hexanediyldiamine salt of/the/ N,N'-hexanediyl-bis-carbamic acid → N,N'-hexanediyl-bis-carbamic acid ; calcium salt

Conditions	Yield
With calcium hydroxide; water at 0℃;

Upstream product

• 124-09-4 1,6-Hexanediamine 
• 124-38-9 carbon dioxide 
• 201230-82-2 carbon monoxide 

Relevant academic research and scientific papers

CARBON DIOXIDE-REVERSIBLY-PROTECTED CHAIN EXTENSION-CROSSLINKING AGENT AND PREPARATION METHOD AND USE THEREOF

Carbon dioxide-reversibly-protected chain extension-crosslinking agents and a preparation method and use thereof are disclosed, The carbon dioxide-reversibly-protected chain extension-crosslinking agents have chemical structures represented by Formula I, Formula II, Formula III or Formula IV, wherein, n, m and p are integers, R is either OCH2CH(CH3) or OCH2CH2, 1≤n≤20, 1≤m≤10, and 1≤p≤10.

CARBONYLATION OF AMINES AND DIAMINES CATALYZED BY NICKEL CARBONYL

The carbonylation of amines and diamines was carried out using nickel carbonyl as the catalyst. reaction of butylamine, diethylamine, and diphenylamine with carbon monoxide all lead exclusively to the corresponding formamide derivative.Benzylamine reacts with carbon monoxide to yield urea and 1,2-diphenylethane.Diamines such as ethylenediamine, 1,2-diaminopropane, and 1,3-propylenediamine react to yield a cyclic condensation product, a cyclic uren, and a carbamic acid.