1430-69-9

Upstream product

• 67-56-1 methanol 
• 51816-27-4 2-(2-bromophenyl)-4,5-dihydro-1,3-oxazole 
• 201230-82-2 carbon monoxide 
• 98945-49-4 N-(2-bromoethyl)phthalimic acid 
• 4376-18-5 Monomethyl phthalate 
• 141-43-5 ethanolamine 
• 186581-53-3 diazomethane 
• 1445-70-1 2-(2-carboxyphenyl)oxazoline 

Relevant academic research and scientific papers

A simple synthesis of 2-substituted oxazolines and oxazines

β-Aminoalcohols react with carboxylic acids in the presence of a zeolite, Ersorb-4, resulting in the formation of oxazoline derivatives in good yields. Similarly, 3-aminopropanol and benzoic acid gave the corresponding 2-phenyloxazine.

Synthesis of isoindolinones via carbonylative cyclisation of 2-(2-bromophenyl)-2-oxazolines by a bimetallic palladium-nickel catalyst system

2-(2-Bromophenyl)-2-oxazolines react with carbon monoxide (3 atm) in alcohol in the presence of a catalytic amount of a bimetallic palladium-nickel catalyst to give the corresponding isoindolinones in high yields.