14300-71-1

Basic information

• Product Name: 5-hydroxy-5-methyl-2(5H)-furanone
• Synonyms: 5-hydroxy-5-methyl-2(5H)-furanone
• CAS NO: 14300-71-1
• Molecular Weight: 114.101
• Mol File: 14300-71-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-5-methyl-2(5H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-5-methyl-2(5H)-furanone(14300-71-1)
• EPA Substance Registry System: 5-hydroxy-5-methyl-2(5H)-furanone(14300-71-1)

Safety Data

• Hazardous Substances Data: 14300-71-1(Hazardous Substances Data)

Upstream product

• 534-22-5 2-methylfuran 
• 1266555-97-8 C₁₄H₁₄O₃ 

Downstream Products

• 4743-82-2 4-oxo-2-pentenoic acid 
• 2833-28-5 trans-4-oxo-2-pentenoic acid 
• 108-28-1 protoanemonin 
• 78-94-4 methyl vinyl ketone 

Relevant articles and documents

Highly efficient continuous flow reactions using singlet oxygen as a "Green" reagent

Described is a new method for the efficient in situ production of singlet oxygen in a simple continuous flow photochemical reactor. The extremely large interfacial area generated by running the biphasic mixture in a narrow channel at a high flow rate ensures high throughput as well as fast and efficient oxidation of various alkenes, 1,3-dienes, and thioethers on a preparative scale.

Prostaglandin endoperoxide H synthase biosynthesis inhibitors

The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).