1430413-00-5

Basic information

• Product Name: 1-(3-((tert-butyldimethylsilyl)oxy)propoxy)cyclohexanecarbonitrile
• Synonyms: 1-(3-((tert-butyldimethylsilyl)oxy)propoxy)cyclohexanecarbonitrile
• CAS NO: 1430413-00-5
• Molecular Weight: 297.513
• Mol File: 1430413-00-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-((tert-butyldimethylsilyl)oxy)propoxy)cyclohexanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-((tert-butyldimethylsilyl)oxy)propoxy)cyclohexanecarbonitrile(1430413-00-5)
• EPA Substance Registry System: 1-(3-((tert-butyldimethylsilyl)oxy)propoxy)cyclohexanecarbonitrile(1430413-00-5)

Safety Data

• Hazardous Substances Data: 1430413-00-5(Hazardous Substances Data)

Upstream product

• 73842-99-6 3-tert-butyldimethylsilyloxy-1-propanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1430413-62-9 C₅H₉NO₂ 
• 111-24-0 1,5-dibromo-pentane 
• 1430412-80-8 2-(3-((TBS)oxy)propoxy)acetonitrile 

Downstream Products

• 1430413-53-8 1-(3-hydroxypropoxy)cyclohexanecarbonitrile 
• 1430413-14-1 3-((1-cyanocyclohexyl)oxy)propyl diethyl phosphate 

Relevant articles and documents

Trianion synthon approach to spirocyclic heterocycles

A variety of spirocyclic heterocycles have been constructed by a double-alkylation and reductive cyclization approach utilizing α-heteroatom nitriles as trianion synthons. The method provides access to heteroatom-substituted spirocycles in a variety of ring sizes that are found in natural products and are important in pharmaceutical lead development and optimization.